On autobiography

I'm having trouble with a comic idea I've been planning. For a long time the general consensus seems to be that for most people (that is people who aren't famous) writing directly about yourself, or something based on yourself is arrogant and poor writing. Don't make Mary-Sues, don't make self-inserts, don't base characters on real friends because you'll offend them... So on and so forth.

I do realise that it's vain and self-indulgent, but I feel like it's something I need to work on for my personal development. The question I suppose, is whether it's possible to turn that into a story that other people will gain something from as well. Will they really ever be interested in the world from my point of view?

Probably not, is the answer I keep coming up with. So devoting time to this is a waste.

Basically it's a slightly surreal slice-of life following a person through the end of high school into university, focusing on events which contribute to her coming to terms with herself. And it's pretty much all lifted straight from my own life. That'll probably make me sound extra arrogant to people who know how low-experience my life is! I must think I'm really important, right? Hopefully the nature of the two main characters' relationship will bring something new to it, but I don't want to give too much away...

I'll probably end up changing the characters and places to depart it all from myself, and never feel quite satisfied as a result. Should I pay attention to my instincts about good storytelling, or should I run with the idea and never look back?